Publications

Peer-reviewed articles

• Siriwongsup, S.; Schmoker, A. S.; Ficarro, S. B.; Marto, J. A.; Kim, J. Chem 2024​, 10, 1306–1315. "Bioorthogonally activated reactive species for target identification."
• Fowler, E.; Kim, J. Chem ​2024, 10, 730–745. "Chemically revertible molecular clasps: Hydroxamic acid-mediated peptide macrocyclization and linearization."
• Kang, D.; Kim, J. Synlett 2024, 35, 145–154. "Enamine N-oxides: Design, Synthesis, and Function in Bioorthogonal Reactions."
• Kang, D.; Wahl, C.; Kim, J. Org. Biomol. Chem. 2022, 20, 9217–9221. "Synthesis of Push-Pull-Activated Ynol Ethers and Their Evaluation in the Bioorthogonal Hydroamination Reaction."
• Kang, D.; Lee, S.; Kim, J. Chem 2022, 8, 2260–2277. "Bioorthogonal Click and Release: A General, Rapid, Chemically Revertible Bioconjugation Strategy Employing Enamine N-oxides."
• Kang, D.; Cheung, S. T.; Kim, J. Angew. Chem. Int. Ed. 2021, 60, 16947–16952. "Bioorthogonal Hydroamination of Push-Pull-Activated Linear Alkynes."
• Kang, D.; Kim, J. J. Am. Chem. Soc. 2021, 143, 5616–5623. "Bioorthogonal Retro-Cope Elimination Reaction of N,N-Dialkylhydroxylamines and Strained Alkynes."
• Kang, D.; Cheung, S. T.; Wong-Rolle, A.; Kim, J. ACS Cent. Sci. 2021, 7, 631–640. "Enamine N-Oxides: Synthesis and Application to Hypoxia-Responsive Prodrugs and Imaging Agents."
• Rivera, S. L.; Espaillat, A.; Aditham, A. K.; Shieh, P.; Muriel-Mundo, C.; Kim, J.; Cava, F.; Siegrist, M. S. Cell Chem. Biol. 2021, 28, 213–220. "Chemically Induced Cell Wall Stapling in Bacteria."
• Shende, V. V.; Khatri, Y.; Newmister, S. A.; Sanders, J. N.; Lindovska, P.; Yu, F.; Doyon, T. J.; Kim, J.; Houk, K. N.; Movassaghi, M.; Sherman, D. H. J. Am. Chem. Soc. 2020, 142, 17413–17424. "Structure and Function of NzeB, a Versatile C–C and C–N Bond-Forming Diketopiperazine Dimerase."
• Hu, J. J.; Liu, X.; Xia, S.; Zhang, Z.; Zhang, Y.; Zhao, J.; Ruan, J.; Luo, X.; Lou, X.; Bai, Y.; Wang, J.; Hollingsworth, L. R.; Magupalli, V. G.; Zhao, L.; Luo, H. R.; Kim, J.; Lieberman, J.; Wu, H. Nat. Immunol. 2020, 21, 736–745. "FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation."
• Marschallinger, J.; Iram, T.; Zardeneta, M.; Lee, S. E.; Lehallier, B.; Haney, M. S.; Pluvinage, J. V.; Mathur, V.; Hahn, O.; Morgens, D. W.; Kim, J.; Tevini, J.; Felder, T. K.; Wolinski, H.; Bertozzi, C. R.; Bassik, M. C.; Aigner, L.; Wyss-Coray, T. Nat. Neurosci. 2020, 23, 194–208. "Lipid droplet accumulating microglia represent a dysfunctional and pro-inflammatory state in the aging brain.​​"
• Haines, B. E.; Nelson, B. M.; Grandner, J. M; Kim, J.; Houk, K. N; Movassaghi, M.; Musaev, D. G. J. Am. Chem. Soc. 2018, 140, 13375–13386. "Mechanism of Permanganate Promoted Dihydroxylation of Complex Diketopiperazines: Critical Roles of Counter-Cation and Ion-Pairing."
• Kim, J.; Bertozzi, C. R. Angew. Chem. Int. Ed. 2015, 54, 15777–15781. “Bioorthogonal Reaction of N-oxide and Boron Reagents.”
• Kim, J.; Movassaghi, M. Acc. Chem. Res. 2015, 48, 1159–1171. “Biogenetically-Inspired Total Synthesis of Epidithiodiketopiperazines and Related Alkaloids.”
• Yang, G.; Lindovska, P.; Zhu, D.; Kim, J.; Wang, P.; Tang, R.-Y.; Movassaghi, M.; Yu, J.-Q. J. Am. Chem. Soc. 2014, 136, 10807–10813. “Pd(II)-catalyzed meta-C–H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template.”
• Coste, A.; Kim, J.; Adams, T. C.; Movassaghi, M. Chem. Sci. 2013, 4, 3191–3197. “Concise Total Synthesis of (+)-Bionectins A and C.”
• Boyer, N.; Morrison, K. C.; Kim, J.; Hergenrother, P. J.; Movassaghi, M. Chem. Sci. 2013, 4, 1646–1657. “Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids.”
• Lathrop, S. P.; Kim, J.; Movassaghi, M. Chimia 2012, 66, 389–393. “Radical Mediated Dimerization and Oxidation Reactions for the Synthesis of Complex Alkaloids.”
• Kim, J.; Movassaghi, M. J. Am. Chem. Soc. 2011, 133, 14940–14943. “Concise Total Synthesis and Stereochemical Revision of (+)-Naseseazines A and B: Regioselective Arylative Dimerization of Diketopiperazine Alkaloids.”
• Kim, J.; Movassaghi, M. J. Am. Chem. Soc. 2010, 132, 14376–14378. “General Approach to Epipolythiodiketopiperazine Alkaloids: Total Synthesis of (+)-Chaetocins A and C and (+)-12,12'-Dideoxychetracin A.”
• Kim, J.; Movassaghi, M. Chem. Soc. Rev. 2009, 38, 3035–3050. “Biogenetically Inspired Syntheses of Alkaloid Natural Products.”
• Kim, J.; Ashenhurst, J. A.; Movassaghi, M. Science 2009, 324, 238–241. “Total Synthesis of (+)-11,11'-Dideoxyverticillin A.”
• Kim, J.; Thomson, R. J. Angew. Chem. Int. Ed. 2007, 46, 3106–3107. “Enantioselective Total Synthesis of the Osteoclastogenesis Inhibitor (+)-Symbioimine.”

Book chapters

1. Kim, J.; Movassaghi, M. (+)-11,11'-Dideoxyverticillin A. In Total Synthesis of Natural Products; Li, J. J.; Corey, E. J., Eds.; Springer-Verlag: Berlin Heidelberg, 2013; pp 211–233.

Patents

1. Boyer, N. C.; Hergenrother, P. J.; Kim, J.; Morrison, K. C.; Movassaghi, M. Compounds, Conjugates and Compositions of Epipolythiodiketopiperazines and Polythiodiketopiperazines. U.S. Patent No. 9353150.

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